財團法人演譯基金會


美兆健康資源中心


  • 「美兆健康資源中心」負責管理三大資料庫--「美兆健康問卷資料庫」、「美兆生化數據資料庫」與「美兆人體生物資料庫」。每一個資料庫均由專人專職負責,以控管資料庫之品質,數據資料亦會定期進行更新,以提供最完整而豐富的醫學研究資源。

美兆健康問卷資料庫


  • 對於以族群為基礎的世代研究而言,「美兆健康問卷資料庫」是一個重要的研究資源。此健康問卷,共分五大類、134題,其內容包含基本資料、個人及家族病史、近況調查、生活習慣及飲食習慣。自1996年至今已經有相當巨量的資料。不同於一般醫學資料庫多是蒐集「病人」之資料,「美兆健康資源中心」的資料與檢體之對象包含廣大的健康與亞健康族群;此外,以「家庭」為單位、會員定期回檢的長期健檢資料,都是「美兆健康資源中心」最重要的特色。



*本圖數據係用台灣地區資料所計算。

美兆生化數據資料庫


  • 「美兆生化數據資料庫」包含100餘項健檢項目之數據,其內容包含身體基本測量、血液檢驗、血糖、血脂、肝功能、腎功能、肺功能、骨密度、腫瘤標記、甲狀腺、發炎指標、糞便、耳鼻喉、眼、心電圖、超音波、胸腹X光、婦科、上腸胃道X光等多項。並且早在1994年就已推行數據電子化。可與「美兆健康問卷資料庫」串連進行統計分析。



*本圖數據係用台灣地區資料所計算。

美兆人體生物資料庫


  • 除健康問卷與健檢資料庫之外,「美兆健康資源中心」設有全台灣第一所經行政院衛生福利部核准通過之民營人體生物資料庫。自2002年起開始採集血液檢體,目前存有來自約7萬多人、9萬多人次,總計超過80萬管的血液樣本,包含多次捐贈者之檢體。按照血清、血漿、血沉中黃層三類分裝,穩定儲存於-80°C低溫冰箱。



*本圖數據係用台灣地區資料所計算。

健康數據資料庫譯碼簿


  •   美兆健康問卷譯碼簿  EXCEL
  •   美兆生化數據譯碼簿  EXCEL

虛擬資料下載


 


研究成果 (2018.01.24 更新)

2018

Lao XQ, Zhang Z, Lau AKH, Chan TC, Chuang YC, Chan J, Lin C, Guo C, Jiang WK, Tam T, Hoek G, Kan H, Yeoh EK, Chang LY. Exposure to Ambient Fine Particulate Matter and Semen Quality in Taiwan. Occup Environ Med. 2018 Feb;75(2):148-154. PMID: 29133596. IF: 3.912

Zhang Z, Guo C, Lau AKH, Chan TC, Chuang YC, Lin C, Jiang WK, Yeoh EK, Tam T, Woo KS, Yan BP, Chang LY, Wong MCS, Lao XQ. Long-Term Exposure to Fine Particulate Matter, Blood Pressure, and Incident Hypertension in Taiwanese Adults. Environ Health Perspect. 2018 Jan 18; 126(1):017008. PMID: 29351544. IF: 9.78

Lao XQ, Liu X, Deng HB, Chan TC, Ho KF, Wang F, Vermeulen R, Tam T, Wong MCS, Tse LA, Chang LY, Yeoh EK. Sleep Quality, Sleep Duration, and the Risk of Coronary Heart Disease: A Prospective Cohort Study With 60,586 Adults. J Clin Sleep Med, 2018 Jan 15;14(1):109-117. PMID: 29198294. IF: 3.429    

Lao XQ, Deng HB, Liu X, Chan TC, Zhang Z, Chang LY, Yeoh EK, Tam T, Wong MCS,  Thomas GN. Increased leisure-time physical activity associated with lower onset  of diabetes in 44 828 adults with impaired fasting glucose: a population-based prospective cohort study. Br J Sports Med. 2018 Jan 13. PMID: 29331993. IF: 6.6

2017

Zhang Z, Hoek G, Chang LY, Chan TC, Guo C, Chuang YC, Chan J, Lin C, Jiang WK, Guo Y, Vermeulen R, Yeoh EK, Tam T, Lau AKH, Griffiths S, Lao XQ. Particulate matter air pollution, physical activity and systemic inflammation in Taiwanese adults. Int J Hyg Environ Health. 2017 Oct 7. PMID: 29030094. IF: 4.643

Deng HB, Tam T, Zee BC, Chung RY, Su X, Jin L, Chan TC, Chang LY, Yeoh EK, Lao XQ. Short sleep duration increases metabolic burden in healthy adults: a population based cohort study. Sleep. 2017 Oct 1;40 (10). PMID: 28977563. IF: 4.923

Zhang Z, Chang LY, Lau AKH, Chan TC, Chieh Chuang Y, Chan J, Lin C, Kai Jiang W, Dear K, Zee BCY, Yeoh EK, Hoek G, Tam T, Qian Lao X. Satellite-based estimates of long-term exposure to fine particulate matter are associated with C-reactive protein in 30034 Taiwanese adults. Int J Epidemiol. 2017 Aug 1; 46 (4):1126-1136. PMID: 28541501. IF: 7.738

Chen SC, Tsai SP, Jhao JY, Jiang WK, Tsao CK, Chang LY. Liver Fat, Hepatic Enzymes, Alkaline Phosphatase and the Risk of Incident Type 2 Diabetes: A Prospective Study of 132,377 Adults. Sci Rep. 2017 Jul 5; 7(1): 4649. PMID: 28680048. IF: 5.228

Wu X, Tsai SP, Tsao CK, Chiu ML, Tsai MK, Lu PJ, Lee JH, Chen CH, Wen C, Chang SS, Hsu CY, Wen CP. Cohort Profile: Taiwan MJ cohort, a half-a-million Chinese with repeated health surveillance data. Int J Epidemiol. 2017 Feb 15. PMID: 28204597. IF: 7.738

2016

Wu X, Wen CP, Ye Y, Tsai M, Wen C, Roth JA, Pu X, Chow WH, Huff C, Cunningham S, Huang M, Wu S, Tsao CK, Gu J, Lippman SM. Personalized Risk Assessment in Never, Light, and Heavy Smokers in a prospective cohort in Taiwan. Scientific Reports. 2016;6:36482. PMID: 27805040 IF: 5.228

Chen CH, Tsai MK, Wen CP. Extending Colorectal Cancer Screening to Persons Aged 40 to 49 Years With Immunochemical Fecal Occult Blood Test: A Prospective Cohort Study of 513,283 Individuals.” J Clin Gastroenterol. 2016 Oct;50 (9):761-8. PMID: 26905605. IF: 3.163

Cheng YY, Huang NC, Chang YT, Sung JM, Shen KH, Tsai CC, Guo HR. Associations between arsenic in drinking water and the progression of chronic kidney disease: A nationwide study in Taiwan. J Hazard Mater. 2016 Sep 14;321:432-439. PMID: 27669384. IF: 4.836

Chuang SY, Chiu TH, Lee CY, Liu TT, Tsao CK, Hsiung CA, Chiu YF. Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: a prospective study. J Hypertens. 2016 Aug 10. PMID: 27512965. IF: 5.062

Muga MA, Owili PO, Hsu CY, Rau HH, Chao JC. Association between Dietary Patterns and Cardiovascular Risk Factors among Middle-Aged and Elderly Adults in Taiwan: A Population-Based Study from 2003 to 2012. PLoS One. 2016;11(7):e0157745. PMID: 27366909. IF: 2.806

Strand LB, Tsai MK, Gunnell D, Janszky I, Wen CP, Chang SS. Self-reported sleep duration and coronary heart disease mortality: A large cohort study of 400,000 Taiwanese adults. Int J Cardiol. 2016 Mar 15;207:246-51. PMID: 26808986. IF: 4.638

Lin WY, Peng CY, Lin CC, Davidson LE, Pi-Sunyer FX, Sung PK, Huang KC. General and Abdominal Adiposity and Risk of Death in HBV Versus Non-HBV Carriers: A 10-Year Population-based Cohort Study. Medicine (Baltimore). 2016 Jan;95(2):e2162. PMID: 26765398. IF: 1.206

Li Z, Yang X, Yang J, Yang Z, Wang S, Sun F, Zhan S. The Cohort Study on Prediction of Incidence of All-Cause Mortality by Metabolic Syndrome. PLoS One. 2016;11(5):e0154990. PMID: 27195697. IF: 2.806

Lo FE, Lu PJ, Tsai MK, Lee JH, Wen C, Wen CP, Wai JP, Tsao CK, Chiang PH, Lyu SY, Ma KL, Chi YC, Li CS, Liu CC, Wu X. The Role of Physical Activity in Harm Reduction among Betel Quid Chewers from a Prospective Cohort of 419,378 Individuals. PLoS One. 2016;11(4):e0152246. PMID: 27044010. IF: 2.806

 

2015

Chiu YF, Hsu CC, Chiu TH, Lee CY, Liu TT, Tsao CK, Chuang SC, Hsiung CA. Cross-sectional and longitudinal comparisons of metabolic profiles between vegetarian and non-vegetarian subjects: a matched cohort study. Br J Nutr. 2015 Oct 28;114(8):1313-20. PMID: 26355190. IF: 3.706

Chang SS, Bjørngaard JH, Tsai MK, Bjerkeset O, Wen CP, Yip PS, Tsao CK, Gunnell D. Heart rate and suicide: findings from two cohorts of 533 000 Taiwanese and 75 000 Norwegian adults. Acta Psychiatr Scand. 2015 Oct 22. PMID: 26493376. IF: 6.79

Sun W, Wen CP, Lin J, Wen C, Pu X, Huang M, Tsai MK, Tsao CK, Wu X, Chow WH. ABO blood types and cancer risk--a cohort study of 339,432 subjects in Taiwan. Cancer Epidemiol. 2015 Apr;39(2):150-6. PMID: 25600007. IF: 3.343

Wen CP, Zhang F, Liang D, Wen C, Gu J, Skinner H, Chow WH, Ye Y, Pu X, Hildebrandt MA, Huang M, Chen CH, Hsiung CA, Tsai MK, Tsao CK, Lippman SM, Wu X. The ability of bilirubin in identifying smokers with higher risk of lung cancer: a large cohort study in conjunction with global metabolomic profiling. Clin Cancer Res. 2015 Jan 1;21(1):193-200. PMID: 25336700. IF: 9.619

 

2014

Chen JH, Wen CP, Wu SB, Lan JL, Tsai MK, Tai YP, Lee JH, Hsu CC, Tsao CK, Wai JP, Chiang PH, Pan WH, Hsiung CA. Attenuating the mortality risk of high serum uric acid: the role of physical activity underused. Ann Rheum Dis. 2014 Jul 22. PMID: 25053714. IF: 12.811

Coresh J, Turin TC, Matsushita K, Sang Y, Ballew SH, Appel LJ, Arima H, Chadban SJ, Cirillo M, Djurdjev O, Green JA, Heine GH, Inker LA, Irie F, Ishani A, Ix JH, Kovesdy CP, Marks A, Ohkubo T, Shalev V, Shankar A, Wen CP, de Jong PE, Iseki K, Stengel B, Gansevoort RT, Levey AS. CKD Prognosis Consortium. Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality. JAMA. 2014 Jun 25;311(24):2518-31. PMID: 24892770. IF: 44.4

You YS, Lin CY, Liang HJ, Lee SH, Tsai KS, Chiou JM, Chen YC, Tsao CK, Chen JH. Association between the metabolome and low bone mineral density in Taiwanese women determined by (1)H NMR spectroscopy. J Bone Miner Res. 2014 Jan;29(1):212-22. PMID: 23775851. IF: 6.284

Chen JH, Chen YC, Mao CL, Chiou JM, Tsao CK, Tsai KS. Association between secreted phosphoprotein-1 (SPP1) polymorphisms and low bone mineral density in women. PLoS One. 2014;9(5):e97428. PMID: 24831687. IF: 2.806

 

2013

Matsushita K, Ballew SH, Astor BC, Jong PE, Gansevoort RT, Hemmelgarn BR, Levey AS, Levin A, Wen CP, Woodward M, Coresh J. Chronic Kidney Disease Prognosis Consortium. Cohort profile: the Chronic Kidney Disease Prognosis Consortium. Int J Epidemiol. 2013 Dec;42(6):1660-8. PMID: 23243116. IF: 7.738

Gunnell D, Chang SS, Tsai MK, Tsao CK, Wen CP. Sleep and suicide: an analysis of a cohort of 394,000 Taiwanese adults. Soc Psychiatry Psychiatr Epidemiol. 2013 Sep;48(9):1457-65. PMID: 23546638. IF: 2.922

Yang XH, Tao QS, Sun F, Cao CK, Zhan SY. [Setting up a risk prediction model on metabolic syndrome among 35-74 year-olds based on the Taiwan MJ Health-checkup Database]. Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Sep;34(9):874-8. PMID: 24331961.

Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, Jafar TH, Heerspink HJ, Mann JF, Matsushita K, Wen CP. Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet. 2013 Jul 27;382(9889):339-52. PMID: 23727170. IF: 11.588

Chen JH, Pan WH, Hsu CC, Yeh WT, Chuang SY, Chen PY, Chen HC, Chang CT, Huang WL. Impact of obesity and hypertriglyceridemia on gout development with or without hyperuricemia: a prospective study. Arthritis Care Res (Hoboken). 2013 Jan;65(1):133-40. PMID: 22933424. IF: 3.319

 

2012

Hallan SI, Matsushita K, Sang Y, Mahmoodi BK, Black C, Ishani A, Kleefstra N, Naimark D, Roderick P, Tonelli M, Wetzels JF, Astor BC, Gansevoort RT, Levin A, Wen CP, Coresh J. Chronic Kidney Disease Prognosis Consortium. Age and association of kidney measures with mortality and end-stage renal disease. JAMA. 2012 Dec 12;308(22):2349-60. PMID: 23111824. IF: 44.4

Fox CS, Matsushita K, Woodward M, Bilo HJ, Chalmers J, Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP, Nelson RG, Chronic Kidney Disease Prognosis Consortium. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet. 2012 Nov 10;380(9854):1662-73. PMID: 23013602. IF: 11.588

Wen CP, Lin J, Yang YC, Tsai MK, Tsao CK, Etzel C, Huang M, Hsu CY, Ye Y, Mishra L, Hawk E, Wu X. Hepatocellular carcinoma risk prediction model for the general population: the predictive power of transaminases. J Natl Cancer Inst. 2012 Oct 17;104(20):1599-611. PMID: 23073549. IF: 12.589

Sun F, Tao QM, Tao QS, Yang XH, Cao CK, Zhan SY. Estimation on the risk of 5-years obesity development among adults aged 30 - 59, based on the Taiwan MJ Health-checkup Database. Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Sep;33(9):921-5. PMID: 23290803.

Yang X, Tao Q, Sun F, Zhan S. The impact of socioeconomic status on the incidence of metabolic syndrome in a Taiwanese health screening population. Int J Public Health. 2012 Jun;57(3):551-9. PMID: 22349293. IF: 2.327

Matsushita K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, Polkinghorne KR, Shankar A, Smith DH, Tonelli M, Warnock DG, Wen CP, Coresh J, Gansevoort RT, Hemmelgarn BR, Levey AS.  Chronic Kidney Disease Prognosis Consortium. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 2012 May 9;307(18):1941-51. PMID: 22570462. IF: 44.4

Chang SS, Wen CP, Tsai MK, Lawlor DA, Yang YC, Gunnell D. Adiposity, its related biologic risk factors, and suicide: a cohort study of 542,088 taiwanese adults. Am J Epidemiol. 2012 Apr 15;175(8):804-15. PMID: 22427611. IF: 4.825

Chuang SY, Chen JH, Yeh WT, Wu CC, Pan WH. Hyperuricemia and increased risk of ischemic heart disease in a large Chinese cohort. Int J Cardiol. 2012 Feb 9;154(3):316-21. PMID: 21862159. IF: 4.638

Chen JH, Yeh WT, Chuang SY, Wu YY, Pan WH. Gender-specific risk factors for incident gout: a prospective cohort study. Clin Rheumatol. 2012 Feb;31(2):239-45. PMID: 21761146. IF: 2.365

Pan WH, Yeh WT, Chen HJ, Chuang SY, Chang HY, Chen L, Wahlqvist ML. The U-shaped relationship between BMI and all-cause mortality contrasts with a progressive increase in medical expenditure: a prospective cohort study. Asia Pac J Clin Nutr. 2012;21(4):577-87. PMID: 23017316. IF: 1.816

 

2011

Wang S, Shu Z, Tao Q, Yu C, Zhan S, Li L. Uric acid and incident chronic kidney disease in a large health check-up population in Taiwan. Nephrology (Carlton). 2011 Nov;16(8):767-76. PMID: 21854506. IF: 1.563

Wen CP, Wai JP, Tsai MK, Yang YC, Cheng TY, Lee MC, Chan HT, Tsao CK, Tsai SP, Wu X. Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet. 2011 Oct 1;378(9798):1244-53. PMID: 21846575. IF: 11.588

Wen CP, Chan HT, Tsai MK, Cheng TY, Chung WS, Chang YC, Hsu HL, Tsai SP, Tsao CK, Man Wai JP, Hsu CC. Attributable mortality burden of metabolic syndrome: comparison with its individual components. Eur J Cardiovasc Prev Rehabil. 2011 Aug;18(4):561-73. PMID: 21450629. IF: 3.606

Mafham M, Emberson J, Landray MJ, Wen CP, Baigent C. Estimated glomerular filtration rate and the risk of major vascular events and all-cause mortality: a meta-analysis. PLoS One. 2011;6(10):e25920. PMID: 22039429. IF: 2.806

Shang P, Shu Z, Wang Y, Li N, Du S, Sun F, Xia Y, Zhan S. Veganism does not reduce the risk of the metabolic syndrome in a Taiwanese cohort. Asia Pac J Clin Nutr. 2011;20(3):404-10. PMID: 21859659. IF: 1.816

 

2010

Wen CP, Tsai MK, Chung WS, Hsu HL, Chang YC, Chan HT, Chiang PH, Cheng TY, Tsai SP. Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking. Cancer Causes Control. 2010 Sep;21(9):1427-35. PMID: 20458529. IF: 2.510

Wen CP, David Cheng TY, Chan HT, Tsai MK, Chung WS, Tsai SP, Wahlqvist ML, Yang YC, Wu SB, Chiang PH, Wen SF. Is high serum uric acid a risk marker or a target for treatment? Examination of its independent effect in a large cohort with low cardiovascular risk. Am J Kidney Dis. 2010 Aug;56(2):273-88. PMID: 20605302. IF: 7.623

Chronic Kidney Disease Prognosis Consortium, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, Gansevoort RT. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet. 2010 Jun 12;375(9731):2073-81. PMID: 20483451. IF: 11.588

Wen CP, Chan TC, Chan HT, Tsai MK, Cheng TY, Tsai SP. The reduction of tuberculosis risks by smoking cessation. BMC Infect Dis. 2010 Jun 7;10:156. PMID: 20529257. IF:2.768

Hsiao FC, Wu CZ, Su SC, Sun MT, Hsieh CH, Hung YJ, He CT, Pei D. Baseline forced expiratory volume in the first second as an independent predictor of development of the metabolic syndrome. Metabolism. 2010 Jun;59(6):848-53. PMID: 20006363. IF:5.777

Sun F, Tao Q, Zhan S. Metabolic syndrome and the development of chronic kidney disease among 118 924 non-diabetic Taiwanese in a retrospective cohort. Nephrology (Carlton). 2010 Feb;15(1):84-92. PMID: 20377775. IF: 1.563

 

Before 2010

Sun F, Tao Q, Zhan S. An accurate risk score for estimation 5-year risk of type 2 diabetes based on a health screening population in Taiwan. Diabetes Res Clin Pract. 2009 Aug;85(2):228-34. PMID: 19500871. IF: 3.639

Sun F, Tao QS, Hsu YH, Zhan SY. Comparison of two diagnostic criteria for metabolic syndrome applied in health check-up population aged 12-19 years in Taiwan. Zhonghua Er Ke Za Zhi. 2009 Jun;47(6):405-9. PMID: 19951463.

Chen JH, Chuang SY, Chen HJ, Yeh WT, Pan WH. Serum uric acid level as an independent risk factor for all-cause, cardiovascular, and ischemic stroke mortality: a Chinese cohort study. Arthritis Rheum. 2009 Feb 15;61(2):225-32. PMID: 19177541. IF: 6.918

Sun F, Tao QS, Zhan SY. Comparison of five different diagnostic criteria on metabolic syndrome applied during physical check-up programs among population aged 35-74, in Taiwan. Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Sep;29(9):925-9. PMID: 19173861.

Wen CP, Cheng TY, Tsai MK, Chang YC, Chan HT, Tsai SP, Chiang PH, Hsu CC, Sung PK, Hsu YH, Wen SF. All-cause mortality attributable to chronic kidney disease: a prospective cohort study based on 462 293 adults in Taiwan. Lancet. 2008 Jun 28;371(9631):2173-82. PMID: 18586172. IF: 11.588

Yang FY, Wahlqvist ML, Lee MS. Body mass index (BMI) as a major factor in the incidence of the metabolic syndrome and its constituents in unaffected Taiwanese from 1998 to 2002. Asia Pac J Clin Nutr. 2008;17(2):339-51. PMID: 18586657. IF: 1.816

Lin WY, Yao CA, Wang HC, Huang KC. Impaired lung function is associated with obesity and metabolic syndrome in adults. Obesity (Silver Spring). 2006 Sep;14(9):1654-61. PMID: 17030977. IF: 3.873

Shen YH, Yang WS, Lee TH, Lee LT, Chen CY, Huang KC. Bright liver and alanine aminotransferase are associated with metabolic syndrome in adults. Obes Res. 2005 Jul;13(7):1238-45. PMID: 16076994.

Chuo SK, Li JC, Tsai WC, Wu DA, Kuo SW, Pei D, Chen SP, Shen DC. Correlations between white blood cell count and metabolic syndrome in middle-age Taiwanese. Endocr Res. 2005;31(1):39-50. PMID: 16238190. IF: 1.408

Chuang SY, Chen CH, Chou P. Prevalence of metabolic syndrome in a large health check-up population in Taiwan. J Chin Med Assoc. 2004 Dec;67(12):611-20. PMID: 15779484. IF: 1.252

Wu DM, Hong Y, Sun CA, Sung PK, Rao DC, Chu NF. Familial resemblance of adiposity-related parameters: results from a health check-up population in Taiwan. Eur J Epidemiol. 2003;18(3):221-6. PMID: 12800946. IF: 7.226

Wu DM, Pai L, Chu NF, Sung PK, Lee MS, Tsai JT, Hsu LL, Lee MC, Sun CA. Prevalence and clustering of cardiovascular risk factors among healthy adults in a Chinese population: the MJ Health Screening Center Study in Taiwan. Int J Obes Relat Metab Disord. 2001 Aug;25(8):1189-95. PMID: 11477504.